The utilization of the ureide carbon of adenine in the biosynthesis of riboflavin in Eremothecium ashbyii.

Studies on the biosynthesis of riboflavin; nitrogen metabolism and flavinogenesis in Eremothecium ashbyii.

The effects of certain purines and pyrimidines upon the production of riboflavin by Eremothecium ashbyii.

Eremothecium ashbyii is one of a number of organisms which produce considerable amounts of riboflavin, most of which is secreted by the cells into the medium (Guilliermond, 1935). The investigations of Schopfer (1944) and Schopfer and Guilloud (1945) resulted in the development of a synthetic medium for this organism which permitted growth and riboflavin production to occur under chemically def...

The incorporation of the pyrimidine ring of adenine into the isoalloxazine ring of riboflavin.

In the biogenesis of riboflavin by the yeast, Eremothecium ashbyii, carbon atoms constituting the pyrimidine ring of adenine were incorporated into the 6,7-dimethylisoalloxazine ring of riboflavin with much greater efficiency than was the 8 position of the purine ring (1). It remained to determine whether the carbon atoms which constitute the pyrimidine ring of the purine are incorporated direc...

Some nutritional requirements for biosynthesis of riboflavin by Eremothecium ashbyii.

Eremothecium ashbyii Guilliermond is a remarkable organism because of its capability of synthesizing relatively large amounts of riboflavin under appropriate conditions. This vitamin is synthesized to a limited extent by a rather wide variety of microorganisms (Pridham, 1952), but those known particularly for their riboflavin producing abilities along with E. a&hbyii are Ashbya gosypi'i (Wicker...

Studies on the synthesis of riboflavin by a mutant yeast, Saccharomyces cerevisiae.

Though the synthesis of riboflavin in large amounts by microorganisms has been encountered, very little is known about the mechani involved in the biosynthesis of this vitamin. A critical examination of the various environmental conditions for different organisms producing this vitamin showed that the optimum conditions for the production of riboflavin varied widely from organism to organism (S...